18 February 2026

2026 (6) Enoch Cook - Mary Foster - Cook Support the newborn American Cause

Enoch Cook was born in Newton MA  in 1744, He died in May 1827 in Westford, Mass. He settled in Groton for a time, about 1770. 
Enoch Cook married Mary Foster (1743-1789) on 21 Feb 1765   * [Vital Records of Newton, Massachusetts] 
His wife Mary Foster was born in 1743, in Newton, Middlesex, MA. 

Genealogy of Fosters in Mass: Mary Foster & Enoch Cook's marriage 1765

(Captain) William Enoch Cook and Mary Foster
The family genealogy passed to Ruth Antilla has Enoch Cook as  >>“William”  Enoch Cook<<.  We can only speculate as to why, for in some of the records I found he is called “Enoch William Cook.” Most records have him as “Enoch Cook.” However, he had a son named “Enoch” – sometimes done to differentiate between father and son within the family.
Their children were: 
1   Lydia Cook 1765–1805
2    Samuel Cook 1767–1858
3   Mary Cook 1769–?
4    Enoch Cook 1771–1830
*5    John Cook 1774–1848
6   Lucy Cook 1777–?
7    Lucy Cook 1779–1840
 8   Sally Cook 1783–1865

American Revolutionary War Service in Massachusetts
Clearly Enoch Cook sided with the “rebel” or American cause in the colony of Massachusetts. He supported it with his ‘life, fortune and sacred honor’ as the following information suggests.
With the alarm on 19 Apr 1775 this company, raised in Groton and Pepperell, Mass, went immediately to Lexington.  
He was a soldier in the Revolutionary war and held the rank of Sergeant in the company of Capt. John Swatelle and the regiment of Col. James Prescott.
Enoch was also in Capt. Edmund Longley's Co., Col. Cogswell's regiment in 1778.  This regiment was on detached service to guard and fortify posts around Boston. 

Enoch Cook's burial information in Westford MA

After the Revolutionary War, the family history papers claim he was a leader in Shay’s Rebellion in western Massachusetts. But I found no records supporting this.

The Cook family owns a Revolutionary period British-flintlock gun?
The family papers of the Cooks (compiled in the late 1900s) mentions a gun from the Revolutionary war, and that it was still in the possession of one of the descendants of Enoch Cook. I searched to verify this but came up with nothing, until I found a newspaper article about a descendant.  A 1901 newspaper article titled “Five Generations of Cooks” says: 

"Abel Cook....was born in the town of Groton, Mass, May 24, 1807. …He is the _grandson of Enoch Cook, who served in the revolutionary war, was present at the surrender of Burgoyne's army and took from an English soldier a flint-lock gun, which is now in his grandson's possession." (where the gun is today, I have no idea)


Enoch Cook's Revolutionary War Loan to Massachusetts
The ending pledge of the Declaration of Independence from England famously says the signers committed their “lives, our fortunes, and our sacred honor” to the cause. 
"Fortunes”  is there because, of course, when the colonies broke from England, they were separate from the mother country. Being "independent" by definition meant they lacked a direct supply of money to pay soldiers or for ammunition, etc.  

Now, there was no Washington DC, no central bank, no currency with anything behind it, no Federal Reserve, and there was no gold to back money. 

Wealthy men, such as Robert Morris Jr of New York was a signer of the Declaration and is considered a financier of the Revolutionary cause. Still, Congress and its colonies had in essence create a “GoFundMe” in each colony to support soldiers, ammo, etc. 

Massachusetts Continental Loan Office
In Oct 1776 to raise money the 2nd Continental Congress authorized a loan office (or Continental loan office) in each of the 13 colonies/states. These colonial offices would accept the loan from colonists (called “subscriptions”) in addition to handling financial matters for the national Treasury.  Each state had its own commissioner of loans, although the officials were technically agents of Congress.
Massachusetts Continental Loan Office issued loan certificates to both men and women. These loans from colonists were called “subscriptions” to a loan office. What was happening was they were contributing to the financing of the colonie's army, rather like War Bonds of WW2. 

Some had subscriptions for the army they served in. Enoch Cook was an officer but he also “subscribed” to the loan. All records of the subscriptions are recorded in loan office's records.
Below is the top of the ledger page Enoch Case's subscription is recorded on. In the yellow box are columns with name, date, number of certificates, certificate #s, and amount in dollars. In the top row I put the date in an orange box (all I can make out is) “1779.” In the pink box is the name of the subscriber; here it is Stephen Greenleaf. The purple box indicates how many certificates he 'subscribed" to: 1 certificate. The blue box next to it indicates Stephen's certificate number, which was 4956. On the right in the green box is the total amount of all certificates he subscribed (at 400 dollars each): he loaned the Commonwealth of Massachusetts 400 dollars (for 1 certificate).

Top of Ledger: Columns with Titles (Massachusetts)

Near the bottom of the ledger page is Enoch Cook's subscription. He too bought 1 certificate, the number was 5023 and loaning the Commonwealth 400 dollars.
 

Enoch Cook's purchase of a subscription on the same ledger page 1779

Discharged from Duty

New England, and Massachusetts in particular, had been so troublesome for such a long time, the British ceased their active military ventures in the colony early in the official war period. The Battle of Brooklyn, NY on Long Island was the first major engagement after the Declaration of Independence was signed July 1776. 

The British forces saved their men and might for the mid-Atlantic and southern colonies for the rest of the war. Enoch Cook was discharged from service in 1779. (Record below) 

Enoch Cook's enlistment and discharge paper (DAR online)
Death and Burial

His wife, Mary (Foster) Cook, died in Groton, Middlesex, MA. Enoch Cook died on 3 May 1827, at the age of 83, and was buried in Fairview Cemetery, Westford, Middlesex, MA


SOURCES:

Marriage record: Vital Records of Newton, Massachusetts, published by the New England Historic Genealogical Society, Boston, Mass, 1905 (Internet Archive)]

 5 Generations of Cooks: Text from "Five Generations of Cooks" published in the Boston Globe Newspaper, 28 Oct 1901, page 2. 
 
 Found in DAR records:

REVOLUTIONARY WAR MUSTER ROLLS, Microfilm Publication: M246; National Archives and Records Administration, Record Group 93: War Department Collection of Revolutionary War Records, 1709-1939

AND

LEDGER RECORDS, Records of the Massachusetts Loan Office, 53.3.2; Microfilm Publications: M925, T783; National Archives and Records Administration, Record Group 53: Records of the Bureau of Public Debt.

Website: Town of Westford Massachusetts, Military burials (town website) accessed Feb 2026 

Family Papers: Cook Family Genealogy (sent by Don F Cook to Ruth Antilla 1980)


2026 (5) James Cook- Lydia Fiske

 James Cook  - Lydia Fiske
 

James Cook, was son of Stephen Cook Jr and Hannah Fuller. He was born in Watertown Mass on 3 Mar 1714 and died in Newton Mass. His father left him a farm in Framingham, and he lived there after his marriage till 1747 when he returned to Newton, MA.

He married in Newton, MA, Lydia Fiske on 24 Nov 1737. 

Lydia was born Jul 1717 in Newton MA and died 9 March 1759 in Newton MA, leaving several young children. (*There are other Fisks and Cooks in Massachusetts and they have to be carefully separated from one another).

The couple had 10 Children (including *Enoch Cook). The first few children were born in Framingham, Ma and the final six in Newton, MA.

 The children of James and Lydia Fiske were: 
1) Jonathan 3 Dec 1738  
2) Lydia 22 Jan 1740 
3) Stephen 24 Jun 1741 
*4) Enoch  B 1744 (see next post)
5) Zebediah Fiske 26 Feb 1746 
6) Elizabeth 6 July 1748 married William Badlam of Sherborn. 
7) Mary 16 Jun 1750 died Nov 1750 
8) Rebecca 18 Jun 1753 married William Flagg 
9) Esther 4 May 1755 
10) James 8 Jan 1758
 

James had his will drawn up in Westborough, Mass in 1774. The will was probate in 1776 Newton Mass in 1776. He died either 1755 or 1776. 

 Mentioned in his will is his wife Mary 
The living children mentioned are: 
1 SONS: Jonathan, Stephen, Enoch, Zebediah Fisk, James 2 DAUGHTERS: Lydia (Bond), Elizabeth, Rebeckah, Esther

3 Mystery children: The bulk of the estate is left to “son and daughter” often shorthand for an son-in-law or daughter-in-law I have not found: Peter and Hannah (possibly a child of a subsequent marriage).

Unsurprisingly, he married at least once (maybe twice) after Lydia died for she left him small children to rear. It is not clear if he had children later, but from reading his will, I suspect either Peter or Hannah was a child of that union.

The probate papers includes an inventory of his estate, in which he mentions his son Enoch Cook--an ancestor and subject of next post.

 

James Cook's Estate Inventory. It names his son Enoch (subject of next post)

Sources 

Historic Homes and Institutions and Genealogical and Personal Memoirs of Worcester County, Massachusetts : With A History of Worcester Society of Antiquity 4; Author: Crane, Ellery Bicknell, 1836-1925,Worcester Historical Museum
 
Probate Records 1648--1924 (Middlesex County, Massachusetts); Author: Massachusetts. Probate Court (Middlesex County) From Ancestry.com

Family Papers: Cook Family History ; Don F Cook sent to Ruth Antilla abt 1980.


13 February 2026

2026 (4) Children of Stephen Cook (Jr) & Hannah Fuller

Stephen Cook Jr was the son of Stephen and Rebecca Flagg. They were the parents of James Cook.

Stephen was born Jan 1683 in Watertown MA and died 1760 in Watertown MA.

He married Hannah Fuller B 1682 in Cambridge Village (later, Newton), MA.  She died Apr 1772 in Watertown, MA. They had at least 8 children including James Cooke. 

Children of Stephen Cook (JR) & Hannah Fuller
*1 James
2 John 

3 Abigail
4 Susanna 
5 Hannah 
6 Mary m. Dix

His will was dated 14 Aug 1757.  His son James was given land adjoining his farm & Stephen's farm in Framingham, MA. He willed his son John Cook all lands, houses, and grist mill.
The rest of estate-real and personal-(egs follow in will).

Stephen Cook (Jr) Will 

Sources:
Family Search.org 
"Massachusetts, Town Clerk, Vital and Town Records, 1626-2001",
Ancestry. com 
The William Ward Genealogy: the History of the Descendants of William Ward of Sudbury, Mass, 1639-1925 

 

2026 (3) Stephen Cook & Rebecca Flagg - Son of Gregory Cook (Parents of Stephen Cook Jr)

STEPHEN COOK & REBECCA FLAGG - GEN 2 

Stephen Cook, son of Gregory Cook and Mary?, was born either in England about 1647 or in Cambridge, MA. He grew up in Cambridge, MA. 

As an adult he settled on the line between Watertown, MA and Newton, MA. Later in his life he moved back  to Cambridge, MA.  

In 1679 Stephen Cook married Rebecca Flagg, daughter of Thomas Flagg. 

They were admitted to the church of Rev Mr Bailey. Stephen became a Deacon of the church, an office held by prestigious members of the congregation.

They were the parents of at least many sons-- which allows for more "Cooks" of Massachusetts to be descended from.  

His wife Rebecca died 20 Jun 1721. Stephen died on 27 July 1738, in Newton, Middlesex, MA, at the age of 91. 

"Deacon" Stephen Cook's grave, Newton, Mass
 They are buried in East Parish Burying Ground, Newton, Middlesex, Massachusetts.

 Rebecca died 20 Jun 1721 and he died in Newton in 1738 at 91 years old. 
Their children were:
1) Mary 2 Dec 1681  bap Watertown 15 Apr 1688
*2) Stephen 9 Jan 1683
3) Isaac 28 Apr 1685
4) John 15 Mar 1686-87 - moved to Preston CT
5) James 23 Jan 1688-89
6) Samuel 3 Dec 1690 settled in Windham CT
7) Peter 10 Aug 1692 
8) Daniel who married in 1722 Mary Jackson (D. of Abraham Jackson)

Sources:

  • Historic Homes and Institutions and Genealogical and Personal Memoirs of Worcester County, Massachusetts : With A History of Worcester Society of Antiquity 4; Author: Crane, Ellery Bicknell, 1836-1925,Worcester Historical Museum 
  •  FindA Grave
  •  Family Search.org




01 February 2026

2026 (2) -Gregory Cook - Where the Cook Line Starts in New England

Gregory Cook - Earliest NE Cook - GEN 1 

From FamilySearch. org: 
Gregory Cooke was born in 1621, in Rattlesden, Suffolk, England. He married Mary White on 25 September 1645, in Suffolk, England. They immigrated and he died on 1 January 1691, in Watertown, Middlesex, Massachusetts, at the age of 70. (Summary edited)
Gregory Cook, born in England about 1625. He worked as a cordwainer or shoemaker. He came to Massachusetts about 1660 and settled in Cambridge MA.

Gregory married 1st Mary __      
She died 17 Aug 1681. 
He married 2nd Widow Susan Goodwin on 1 November 1681. (After his death she married Henry Spring).
 
The only known names of his children were Susanna Cook of Newton who died 13 Nov 1674, and Stephen Cook.
 
 In 1672 he bought the nearby Dummer farm, or 112 acres of it, adjoining his farm. 
In 1663 he bought land from Abraham Williams including a house on the highway from Watertown to Roxbury, near Edward Jackson Sr and near what is now Newton Centre near the Watertown line. While Cook's house was torn down in 1823, but it was handed down to his son Stephen who likely lived in it.

Gregory was a prominent man in public life. He was a constable in Cambridge Village in 1667, selectman of Mendon 1669 to 1670, and proprietor of 40 acres of land there. 
 
But he did not remain there long. He was a selectman of Watertown in 1673-1678-1679-1681-1684. He was on a coroner's jury in Watertown June 15, 1674. He died January 1, 1691.
 
His son Stephen administered the estate, the inventory gave the value of the estate as one hundred and ninety-one pounds.

Source 
Historic Homes and Institutions and Genealogical and Personal Memoirs of Worcester County, Massachusetts : With A History of Worcester Society of Antiquity 4; Author: Crane, Ellery Bicknell, 1836-1925,Worcester Historical Museum

13 January 2026

2026 (1) - MURDER? John Cook Jr and his wives.

 MURDER? John Cook Jr / Roxanna Lane

As a genealogist you read all sorts of human experiences: the good, the bad and the ugly. But I never expected to find someone indicted and tried for murder.
 
John Cook Jr, the father of John Levi Cook (subject of post #1), reminds me of how little I know his John Levi Cook's childhood.
 
John Cook Jr was born in Winchendon, Mass, on 5 Mar 1805, to Anna Beal and John Cook. 
 Winchendon is close to the New Hampshire state line, as is Ashburnham, MA, the location he settled in. In the 1845 map below, Winchendon is just left of the green area (which is Ashburnham). You see "Rindge" and "New Ipswich" --those towns are in New Hampshire.
In March 1832 he and Roxanna Lane announced intentions to wed. He was 27 years old at the time, she was 39 years old. (Somewhat unusual for an older woman to marry a man more than 10 years younger.)  Because it was not customary to keep your maiden name, Roxanna had never been married. (It's possible either one or both had once been engaged, but no evidence of a marriage). 
 
They were married 3 April 1832. 
 
Roxana's father held much land in Ashburnham--he acquired land from relatives through the years, and eventually was prosperous as a result. (it's quite possible he established businesses on the land).
 
John Cook's and his wife had a baby girl they named Sarah Roxanna Cook on 6 Oct 1833, when Roxanna was 40 years old.
 
1834 - Quite a year. 
Unfortunately the baby's mother, Roxanna, died 24 Feb 1834, before the child was a year old. A few months later, his father-in-law, Benjamin Lane, makes a will. 
---- 
8 Apr 1834  
A summary of Benjamin Lane's will.  
His will provides $100 to his infant granddaughter, Sarah Roxanna, the daughter of the deceased Roxanna, to be paid one year after his decease.  "And it is my will that her father should be appointed her guardian to manage and to take care of her legacy." (that would be John Cook). Other property was divided amongst the sons. All daughters, who were married would have one share. 

There was a yet unmarried daughter, Melinda, "who lives with in my family" to be included in the one share equally divided. Moreover,"The several sums which I have advanced to my said daughter (and may hereafter advance to them) and which are on my books to be deducted from their portions respectively."

Throughout the entire will, Benjamin is clear that his "books" will reflect the amount to be deducted, whether for the Howard children or Melinda. It is a meticulous will--it was so specific it made me wonder about the family relationships. He seemed to have a strong desire that no one be untreated unfairly in money once he had died and no longer had oversight.
 
1834 was not yet over: Before the year was out, John Cook remarries.
 
John Cook Jr was 29 when he married Cynthia Metcalf. Cynthia was 17 when she married John Cook on 12 November 1834. 

Nothing is very unusual here except he marries a woman much older than he, then after her death, his second wife is 12 years younger than he. 
We're not judging, just noting.


As I mentioned, the will of Benjamin Lane had been drawn up in April of that year. He, the father of the deceased Roxanna Lane Cook, died 1 1/2 years after making his will, in Dec 1835.
 
John Cook Jr and wife 2, Cynthia Metcalf have three children:
 1 George W Cook 1836–1855
 2 Martha Jane Cook 1840–1910
 3*John Levi Cook 1841–1910 (*ancestor)
 
But Cynthia, his 2nd wife, dies in 1844, when the youngest is only 3 years old. They were married for 10 years.


So far their life has been sad, but now it gets strange. In 1846, John Cook is charged with murdering his 1st wife, Roxanna Lane. I could not find the details. Apparently he was tried in Worcester (the county seat). 

1848 was a bad, bad year for John Cook Jr

On February 21-25, 1834, in Ashburnham, Worcester County, John Cook Jr. was accused of mixing and administering poison (white arsenic) to his wife, Roxanna Cook, ultimately resulting in her death on February 25, 1834.

The case was brought before the Court of Common Pleas in Worcester, with the indictment returned by the Grand Jury in September. Proceeding/court trial continuing into October and December 1848.

In October and December 1848, John Cook the younger stood trial in Worcester County after being indicted for murdering his wife by poison. He was found not guilty by a jury on December 7, 1848, leading to his discharge.

Dates

  • February 21–25, 1834 (events involving John and Roxanna Cook)
  • September 1848 (Grand Jury indictment, Court of Common Pleas)
  • October and December 1848 (jury trial held and judgment/proceedings)

Names and Relationships

  • John Cook Jr., husband of Roxanna Cook (accused)
  • Roxanna [Lane] Cook, wife of John Cook Jr. (deceased)

Names and Relationships

  • John Cook Jr (called, “the younger” defendant in the trial)
  • Benjamin F. Thomas (assigned counsel for John Cook)
  • Milton Whitney (assigned counsel for John Cook)
  • John W. Lincoln (Sheriff)
  • Isaac Davenport (jury foreman)
  • Other jurors: Edward Aldrich, Gilman Day, Asa E. Edmunds, Joseph M. Green, Asa Kilburn, Asa Marcan, Samuel Patrick, Henry B. Pratt, Jesse Spaulding, Alvah A. Stone, Isaac N. Stone (jurors in the trial)

Text of court documents (original docs below text)

Page 1

Commonwealth . vs Cook October , 1848, by adjournment , December , 1848 .

The Jurors for the Commonwealth aforesaid , on their oath present That John Cook the younger of Winchendon in the County of Worcester, yeoman, contriving and intending one Roxanna Cook wife of said John Cook , with person feloniously willfully and of his malice aforethought to kill and murder , on the twenty first day of February in the year of our Lord one thousand Eight hundred and thirty four and on divers days and times between that day and the twenty fifth day of the same of February , willfully , feloniously and of his malice aforethought did mix and mingle a large quantity of deadly poison, to wit, White Arsenic in certain food and drink which had during the time aforesaid, at divers days and times been prepared for the use of the said Roxanna Cook to be eaten and drunk, by her, the said Rosanna Cook, he the said John Cook then and there well knowing that the said food and drink, with which he the said John Cook did so my and mingle the said deadly poison as aforesaid was then and there prepared for the use of the said Roxanna Cook with intent to be administered to and taken by her for her eating and drinking the same, and he the said John Cook then and there well knowing that the said White Arsenic so as a?id by him mixed and mingled in said food and drink to be a deadly poison, and the said food and drink, with which said deadly poison was so mixed and mingled as aforesaid, afterwards to wit on said twenty first day of February, and on said divers days and times were delivered to said Roxanna Cook and taken by her to be eaten and drank by her, and she the said Roxanna Cook not knowing the said poison to be mixed and mingled with said food and drink, did afterwards to wit, on said twenty first day of February and on said divers days and times , there eat, drink and swallow down several large quantities of said deadly poison so mixed and mingled as aforesaid with said food and drink, and the said John Cook that he might the more certainly and speedily destroy the life of the said Roxanna Cook on the twenty third day of said February , with force and arms at Ashburnham aforesaid October, 1848 , by adjournment , December, 1848, did, knowingly, willfully, feloniously and of his malice aforethought did mix and mingle a large quantity of deadly poison, to wit White Arsenic , with certain sling, he the said John Cook then and there well knowing the said White Arsenic to be a deadly poison, and afterwards to wit , on said twenty third day of said February at said Ashburnham the said person so mixed and mingled as aforesaid with the ring aforesaid feloniously willfully and of his malice aforethought, the said John Cook did give and administer to the said Rosanna Cook to take drink and swallow down , and the said Roxanna Cook not knowing the person aforesaid in the sting aforesaid to have been mixed and mingled as aforesaid afterwards , to wit , on said twenty third day of February aforesaid , at said Ashburnham , the said poison so as aforesaid mixed and mingled , by the procurement, and persuasion of said John Cook did take drink and swallow down, and the said Roxanna Cook of the poison aforesaid and by the operation thereof, on said twenty third day of February aforesaid at said Ashburnham , became and was sick and greatly distempered in her body, of which said sickness and distemper of body occasioned by the eating drinking and swallowing down into the body of her the said Roxanna Cook of the person aforesaid so as aforesaid mixed and mingled with the food drink and sling aforesaid she the said Roxanna Cook from the said several days and times on which she had so eaten drank and swallowed down the person as aforesaid until the twenty fifth day of February aforesaid did then and there languish and languishing did live and on said twenty fifth day of February aforesaid at Ashburnham aforesaid , she the said Roxanna Cook of the poison aforesaid so eaten drunk and swallowed down as aforesaid and of the sickness and distemper aforesaid , thereby occasioned, did die . And so the jurors aforesaid upon their oath aforesaid do say that the said John Cook , he the said Rosanna Cook in manner and form , and by the means aforesaid, then and there feloniously willfully and of his malice aforethought, did kill and murder, against the peace of said Commonwealth and contrary to the form of the State in such case made and provided. This Indictment was returned by the Grand Jury into the Court of Common Pleas, at a term thereof holden at Worcester within and for the said County of Worcester on the fourth Monday in September last.

PAGE 2

1848, by adjournment, December 1848

The Court , that , as soon as might be , the above named John Cook the younger , should be served with a copy of the aforesaid Indictment, with the order thereon , by the Sheriff of said County or his Deputy , and that in manner aforesaid , the said John Cook the your or should be notified that the said Indictment would be entered at the Term of the Supreme Judicial Court, next to be holden at Worcester , within and for the County of Worcester , on the first Tuesday of October then next, then and there to be heard and determined as the law directs . And it appearing to the Court here that the said Indictment charged the said John Cook the younger with a crime punishable with death.

It was ordered by the Court there, that the said Indictment, together with the several orders of that Court, made thereon , should be transmitted to the Supreme Judicial Court , next to be holden at Worcester , within and for the County of Worcester , on the first Tuesday of October , then next , there to be entered and proceeded upon according to law. And the Court there further ordered, that the said John Cook the younger , who was then in the custody of the Sheriff of said County , in our jail at Worcester , in said County , should be held in confinement in our said Jail, until he should be delivered therefrom by due course of law .

This Indictment was accordingly transmitted to this Court, and entered in the same Court for this County at October Term, 1848 when the said John Cook the younger , came before the Court , under the custody of the Sheriff of said County , and was set to the Bar and arraigned upon said Indictment, and having been enquired of how he would acquit himself thereof, the same said that thereof he was not guilty, and thereof for trial put himself upon the Country , and at the request of the said John Cook the younger, Benjamin F. Thomas and Milton Whitney , Esquires , were assigned by the Court , as counsel for the said Cook . and thereupon the said John Cook the younger, was remanded to the Jail in said County , from whence he was taken , and on motion of the said Cook the trial of this Indictment was postponed to the fifth day of December 1848 , to which day this Court was adjourned and afterwards , on said fifth day of December this Court was further adjourned to the seventh day of the same December and now in this present adjourned Term , to wit on the seventh day of December 1848 .

The time assigned for the trial of the said John Cook , the younger , before the Court here , again comes the said John Cook the younger , under the custody of the Sheriff of said County , and is placed at the Bar , and the said Thomas and Whitney October , 1848 , by adjournment , December , 1848 . assigned by the Court as Counsel for the said Cook , also appear a Jury is thereupon empannelled to try said Indictment , to wit ; Isaac Davenport , who is appointed Foreman by the Court and Feblows , namely , Edward Aldrich , Gilman Day , Asa E. Edmunds , Joseph M. Green , Asa Kilburn , Asa Marcan , Samuel Patrick Henry B. Pratt Jesse Spaulding , Alvah A. Stone , & Isaac N. Stone who being sworn to speak the truth of and concerning the premises , after hearing all matters and things , in relation to the same , return their verdict therein , and upon their oath say , that the said John Cook the younger, is not guilty ;

It is therefore ordered by the Court that the said John Cook the younger, be discharged of said Indictment and permitted to go so thereof discharged, without delay. Ordered , that the sum of One Hundred Twelve dollars and Forty Six cents , be paid out of the County Treasury , to John W. Lincoln for attendance as sheriff of himself and deputies at October last and this adjournment and disbursements , as by the account on file , examined and allowed. (END)


He was acquitted but she had been dead for 15 years by the time he was acquitted.
 A newspaper clipping adds unsubstantiated details:
Apparently the first wife's sister, Melinda (who had been unmarried at the time) was "the dreaming witness" who believed John Cook poisoned Roxanna.
It does not specify which sister contradicted her in "material points." But the jury did not deliberate long. 
 (One has to wonder what would lead Melinda to make an accusation to lead to an arrest at this time, so long after her death?)  
Original Court Record 1/2 (Worcester County, MA)

.
Court Record with Verdict highlighted 2/2 (Source: FamilySearch. org)